Search on: SOLUTE CARRIER FAMILY 12, MEMBER 3 
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Descriptor English:   Solute Carrier Family 12, Member 3 
Descriptor Spanish:   Miembro 3 de la Familia de Transportadores de Soluto 12 
Descriptor Portuguese:   Membro 3 da Família 12 de Carreador de Soluto 
Tree Number:   D12.776.157.530.450.625.374.500
Definition English:   Na-Cl cotransporter in the convoluted segments of the DISTAL KIDNEY TUBULE. It mediates active reabsorption of sodium and chloride and is inhibited by THIAZIDE DIURETICS. 
Entry Combination - descr/qualif English:   Solute Carrier Family 12, Member 3/antagonists & inhibitors use Sodium Chloride Symporter Inhibitors
 
See Related English:   Gitelman Syndrome
 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   55322 
Unique Identifier:   D064486 

Occurrence in VHL: 		 

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